MEWpy - Metabolic Engineering in Python
Project description
MEWpy
MEWpy is an integrated Metabolic Engineering Workbench for strain design optimization. It offers methods to explore different classes of constraint-based models (CBM) for:
- Simulation: allows to simulate steady-state metabolic models, considering different formulations (e.g., GECKO, ETFL) and kinetic models;
- Optimization: performs Evolutionary Computation based strain design optimization by knocking out (KO) or over/under expressing (OU) reactions, genes, or enzymes.
- Omics data integration (eFlux, GIMME, iMAT);
- Regulatory networks integration (rFBA, srFBA)
MEWPy currently supports REFRAMED and COBRApy simulation environments.
Documentation
For documentation and API please check: https://mewpy.readthedocs.io <https://mewpy.readthedocs.io>_
Installation
pip install mewpy
Credits and License
Developed at:
- Centre of Biological Engineering, University of Minho (2019-)
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